Article
The nitric oxide synthase 3 gene polymorphisms and their association with deep vein thrombosis in Asian Indian patients.
Clinica chimica acta; international journal of clinical chemistry - 2 May 2010
Akhter Mohd Suhail, Biswas Arijit, Ranjan Ravi, Sharma Amit, Kumar Sunil, Saxena Renu
Abstract excerpt
BACKGROUND: Endothelium derived nitric oxide is formed from l-arginine by endothelial nitric oxide synthase encoded by the nitric oxide synthase 3 (NOS3) gene. Nitric oxide possesses a variety of protective effects on endothelial cells and therefore NOS3 is a logical candidate gene to be investigated for the susceptibility of deep vein thrombosis (DVT). METHODS: One hundred consecutive patients (M: F=56:44) with...
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