Article
Contrasting evolutionary histories of MHC class I and class II loci in grouse--effects of selection and gene conversion.
Heredity - 1 May 2016
Minias P, Bateson Z W, Whittingham L A, Johnson J A, Oyler-McCance S, Dunn P O
Abstract excerpt
Genes of the major histocompatibility complex (MHC) encode receptor molecules that are responsible for recognition of intracellular and extracellular pathogens (class I and class II genes, respectively) in vertebrates. Given the different roles of class I and II MHC genes, one might expect the strength of selection to differ between these two classes. Different selective pressures may also promote different rates...
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