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Article

Characterisation of major histocompatibility complex class I genes in Japanese Ranidae frogs.

Immunogenetics - 1 Nov 2016

Lau Quintin, Igawa Takeshi, Komaki Shohei, Satta Yoko

Abstract excerpt

The major histocompatibility complex (MHC) is a key component of adaptive immunity in all jawed vertebrates, and understanding the evolutionary mechanisms that have shaped these genes in amphibians, one of the earliest terrestrial tetrapods, is important. We characterised MHC class I variation in three common Japanese Rana species (Rana japonica, Rana ornativentris and Rana tagoi tagoi) and identified a total of...

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Amino Acid Sequence
Biological Evolution
Genetic Variation
Histocompatibility Antigens Class I
Phylogeny

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Selection, Genetic

Sequence Homology, Amino Acid

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Identifiers

PMID: 27418258
DOI: 10.1007/s00251-016-0934-x
PMCID: PMC5056945

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