Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Meta-analysis of major histocompatibility complex (MHC) class IIA reveals polymorphism and positive selection in many vertebrate species.

Molecular ecology - 1 Dec 2022

Dearborn Donald C, Warren Sophie, Hailer Frank

Abstract excerpt

Pathogen-mediated selection and sexual selection are important drivers of evolution. Both processes are known to target genes of the major histocompatibility complex (MHC), a gene family encoding cell-surface proteins that display pathogen peptides to the immune system. The MHC is also a model for understanding processes such as gene duplication and trans-species allele sharing. The class II MHC protein is a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fishes
Share to Genes, MHC Class II
Share to Major Histocompatibility Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mammals

Share to Phylogeny

Share to Polymorphism, Genetic

Share to Selection, Genetic

Share to Vertebrates

Source

Open in PubMed Open full text

Identifiers

PMID: 36208104
DOI: 10.1111/mec.16726
PMCID: PMC9729452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Meta-analysis of major histocompatibility complex (MHC) class IIA reveals polymorphism and positive selection in many vertebrate species.PMID 36208104Read ↗

Evolution of MHC IIB Diversity Across Cichlid Fish Radiations.Semantic proximity Read ↗

MHCtools 1.5: Analysis of MHC Sequencing Data in R.Semantic proximity Read ↗

Advances in the Evolutionary Understanding of MHC Polymorphism.Semantic proximity Read ↗

Characterization of 40 full-length MHC class IIA functional alleles in miiuy croaker: Polymorphism and positive selection.Semantic proximity Read ↗

MHC studies in nonmodel vertebrates: what have we learned about natural selection in 15 years?Semantic proximity Read ↗

Comparative MHC nomenclature: report from the ISAG/IUIS-VIC committee 2018.Semantic proximity Read ↗

A pan-cetacean MHC amplicon sequencing panel developed and evaluated in combination with genome assemblies.Semantic proximity Read ↗

A global analysis of selection at the avian MHC.Semantic proximity Read ↗

Characterisation of major histocompatibility complex class I genes in Japanese Ranidae frogs.Semantic proximity Read ↗

Characterization of MHC class IIB for four endangered Australian freshwater fishes obtained from ecologically divergent populations.Semantic proximity Read ↗

Evolution of MHC class II allelic diversity.Semantic proximity Read ↗

Characterization of both major histocompatibility complex classes in a wild social mammal: the banded mongooseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.