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Article

Genetic diversity of MHC class I loci in six non-model frogs is shaped by positive selection and gene duplication.

Heredity - 1 Sept 2012

Kiemnec-Tyburczy K M, Richmond J Q, Savage A E, Lips K R, Zamudio K R

Abstract excerpt

Comparative studies of major histocompatibility complex (MHC) genes across vertebrate species can reveal the evolutionary processes that shape the structure and function of immune regulatory proteins. In this study, we characterized MHC class I sequences from six frog species representing three anuran families (Hylidae, Centrolenidae and Ranidae). Using cDNA from our focal species, we amplified a total of 79...

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Identifiers

PMID: 22549517
DOI: 10.1038/hdy.2012.22
PMCID: PMC3424922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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