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Article

Analysing multiple types of molecular profiles simultaneously: connecting the needles in the haystack.

BMC bioinformatics - 9 Feb 2016

Menezes Renée X, Mohammadi Leila, Goeman Jelle J, Boer Judith M

Abstract excerpt

BACKGROUND: It has been shown that a random-effects framework can be used to test the association between a gene's expression level and the number of DNA copies of a set of genes. This gene-set modelling framework was later applied to find associations between mRNA expression and microRNA expression, by defining the gene sets using target prediction information. METHODS AND RESULTS: Here, we extend the model...

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Identifiers

PMID: 26860128
DOI: 10.1186/s12859-016-0926-8
PMCID: PMC4746904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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