Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A regression model for estimating DNA copy number applied to capture sequencing data.

Bioinformatics (Oxford, England) - 15 Sept 2012

Rigaill Guillem J, Cadot Sidney, Kluin Roelof J C, Xue Zheng, Bernards Rene, Majewski Ian J, Wessels Lodewyk F A

Abstract excerpt

MOTIVATION: Target enrichment, also referred to as DNA capture, provides an effective way to focus sequencing efforts on a genomic region of interest. Capture data are typically used to detect single-nucleotide variants. It can also be used to detect copy number alterations, which is particularly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Breast Neoplasms
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Genomics

Share to Linear Models

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 22796958
DOI: 10.1093/bioinformatics/bts448

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22796958-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A regression model for estimating DNA copy number applied to capture sequencing data.PMID 22796958Read ↗

CoNCoS: copy number estimation in cancer with controlled support.Semantic proximity Read ↗

CARAT: a novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays.Semantic proximity Read ↗

A single-array preprocessing method for estimating full-resolution raw copy numbers from all Affymetrix genotyping arrays including GenomeWideSNP 5 & 6.Semantic proximity Read ↗

Analysing multiple types of molecular profiles simultaneously: connecting the needles in the haystack.Semantic proximity Read ↗

Rawcopy: Improved copy number analysis with Affymetrix arraysSemantic proximity Read ↗

Using high-density DNA methylation arrays to profile copy number alterations.Semantic proximity Read ↗

A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays.Semantic proximity Read ↗

BACOM: in silico detection of genomic deletion types and correction of normal cell contamination in copy number data.Semantic proximity Read ↗

A robust model for read count data in exome sequencing experiments and implications for copy number variant calling.Semantic proximity Read ↗

A single-sample method for normalizing and combining full-resolution copy numbers from multiple platforms, labs and analysis methods.Semantic proximity Read ↗

ITALICS: an algorithm for normalization and DNA copy number calling for Affymetrix SNP arrays.Semantic proximity Read ↗

CNAseg--a novel framework for identification of copy number changes in cancer from second-generation sequencing data.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.