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DNA Inversion Regulates Outer Membrane Vesicle Production in Bacteroides fragilis

9 Feb 2016

Abstract excerpt

Phase changes in Bacteroides fragilis, a member of the human colonic microbiota, mediate variations in a vast array of cell surface molecules, such as capsular polysaccharides and outer membrane proteins through DNA inversion. The results of the present study show that outer membrane vesicle (OMV) formation in this anaerobe is also controlled by DNA inversions at two distantly localized promoters, IVp-I and...

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PMID: 26859882
DOI: 10.1371/journal.pone.0148887

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