Article

High-throughput single-cell sequencing of multiple invertible promoters reveals a strong determinant of bacterial population heterogeneity

2022-11-02

Abstract excerpt

<h4>ABSTRACT</h4> Population heterogeneity can promote bacterial fitness in response to unpredictable environmental conditions. Human gut symbiont Bacteroides spp., displays variability in single cell surface architectures by combinatorial regulation of promoter inversions that drive expression of capsular polysaccharides (CPS). Using high-throughput single-cell sequencing, we reveal population heterogeneity gen...

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Literature Corpus work: 7a165f95-8f44-53af-88c1-6ac0c2ecf8ff
DOI: 10.1101/2022.10.31.514637

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