Article
Selective breeding for high voluntary exercise in mice increases maximal (V̇O2,max) but not basal metabolic rate.
The Journal of experimental biology - 1 Aug 2023
Schwartz Nicole E, McNamara Monica P, Orozco Jocelyn M, Rashid Jaanam O, Thai Angie P, Garland Theodore
Abstract excerpt
In general, sustained high rates of physical activity require a high maximal aerobic capacity (V̇O2,max), which may also necessitate a high basal aerobic metabolism (BMR), given that the two metabolic states are linked via shared organ systems, cellular properties and metabolic pathways. We tested the hypotheses that (a) selective breeding for high voluntary exercise in mice would elevate both V̇O2,max and BMR,...
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