Article
Quantitative trait loci associated with maximal exercise endurance in mice.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Jul 2007
Lightfoot J Timothy, Turner Michael J, Knab Amy Kleinfehn, Jedlicka Anne E, Oshimura Tomohiro, Marzec Jacqui, Gladwell Wesley, Leamy Larry J, Kleeberger Steven R
Abstract excerpt
The role of genetics in the determination of maximal exercise endurance is unclear. Six- to nine-week-old F2 mice (n = 99; 60 female, 39 male), derived from an intercross of two inbred strains that had previously been phenotyped as having high maximal exercise endurance (Balb/cJ) and low maximal exercise endurance (DBA/2J), were treadmill tested to estimate exercise endurance. Selective genotyping of the F2...
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