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Identification of novel advanced glycation end products receptor gene variants associated with colorectal cancer in Tunisians: A case-control study.

Gene - 5 Sept 2020

Bedoui Sinda A, Barbirou Mouadh, Stayoussef Mouna, Dallel Meriem, Mokrani Amina, Makni Lamia, Mezlini Amel, Bouhaouala-Zahar Balkiss, Yacoubi-Loueslati Besma, Almawi Wassim Y

Abstract excerpt

A central role for advanced glycation end products (AGE) and their receptor (RAGE) in the pathogenesis of multiple cancer types, including colorectal cancer (CRC) was reported. We investigated the association between CRC and rs2853807, rs77170610, rs184003, rs1035798, rs2070600, , , and RAGE gene (AGER) polymorphic variants. Study subjects comprised 293 CRC patients [186 colon cancer...

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PMID: 32544495
DOI: 10.1016/j.gene.2020.144893

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