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Article

Genetic Variants Within Molecular Targets of Antipsychotic Treatment: Effects on Treatment Response, Schizophrenia Risk, and Psychopathological Features.

Journal of molecular neuroscience : MN - 1 Jan 2018

Calabrò Marco, Porcelli Stefano, Crisafulli Concetta, Wang Sheng-Min, Lee Soo-Jung, Han Changsu, Patkar Ashwin A, Masand Prakash S, Albani Diego, Raimondi Ilaria, Forloni Gianluigi, Bin Sofia, Cristalli Carlotta, Mantovani Vilma, Pae Chi-Un, Serretti Alessandro

Abstract excerpt

Schizophrenia (SCZ) is a common and severe mental disorder. Genetic factors likely play a role in its pathophysiology as well as in treatment response. In the present study, we investigated the effects of several single nucleotide polymorphisms (SNPs) within 9 genes involved with antipsychotic (AP) mechanisms of action. Two independent samples were recruited. The Korean sample included 176 subjects diagnosed with...

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Identifiers

PMID: 29164477
DOI: 10.1007/s12031-017-1002-1

Genes

CHRNA7
COMT
MAPK1
SIGMAR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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