Article
Sulfotransferase 1A1 (SULT1A1) polymorphism and bladder cancer risk: a case-control study.
Cancer letters - 8 Dec 2003
Zheng Leizhen, Wang Yunfei, Schabath Matthew B, Grossman H Barton, Wu Xifeng
Abstract excerpt
Sulfotransferases (SULT) catalyze both the bioactivation and detoxification of a wide range of promutagens and procarcinogens. SULT1A1 appears to be an important phenol SULT because of its abundance and distribution in many tissues and wide substrate specificity. The SULT1A1 gene possesses a G-->A polymorphism that results in an Arg to His amino acid substitution, and the His(213) allele has been shown to have...
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