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Article

Structural characterization of GASDALIE Fc bound to the activating Fc receptor FcγRIIIa.

Journal of structural biology - 1 Apr 2016

Ahmed Alysia A, Keremane Sravya R, Vielmetter Jost, Bjorkman Pamela J

Abstract excerpt

The Fc region of Immunoglobulin G (IgG) initiates inflammatory responses such as antibody-dependent cell-mediated cytotoxicity (ADCC) through binding to activating Fc receptors (FcγRI, FcγRIIa, FcγRIIIa). These receptors are expressed on the surface of immune cells including macrophages, dendritic cells, and natural killer cells. An inhibitory receptor, FcγRIIb, is expressed on macrophages and other myeloid...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26850169
DOI: 10.1016/j.jsb.2016.02.001
PMCID: PMC4769027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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