Article
Copy number alterations and neoplasia-specific mutations in MELK, PDCD1LG2, TLN1, and PAX5 at 9p in different neoplasias.
Genes, chromosomes & cancer - 1 Jul 2014
Sarhadi Virinder Kaur, Lahti Leo, Scheinin Ilari, Ellonen Pekka, Kettunen Eeva, Serra Massimo, Scotlandi Katia, Picci Piero, Knuutila Sakari
Abstract excerpt
Genetic alterations affecting 9p are commonly present in many cancer types and many cancer-related genes are located in this chromosomal region. We sequenced all of the genes located in a 32Mb region of 9p by targeted next generation sequencing (NGS) in 96 patients with different cancer types, including acute lymphoblastic leukemia, bone malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma,...
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