Article
Adaptive Remodeling of the Bacterial Proteome by Specific Ribosomal Modification Regulates Pseudomonas Infection and Niche Colonisation.
PLoS genetics - 1 Feb 2016
Little Richard H, Grenga Lucia, Saalbach Gerhard, Howat Alexandra M, Pfeilmeier Sebastian, Trampari Eleftheria, Malone Jacob G
Abstract excerpt
Post-transcriptional control of protein abundance is a highly important, underexplored regulatory process by which organisms respond to their environments. Here we describe an important and previously unidentified regulatory pathway involving the ribosomal modification protein RimK, its regulator proteins RimA and RimB, and the widespread bacterial second messenger cyclic-di-GMP (cdG). Disruption of rimK affects...
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