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Article

Lysobacter PilR, the Regulator of Type IV Pilus Synthesis, Controls Antifungal Antibiotic Production via a Cyclic di-GMP Pathway.

Applied and environmental microbiology - 1 Apr 2017

Chen Yuan, Xia Jing, Su Zhenhe, Xu Gaoge, Gomelsky Mark, Qian Guoliang, Liu Fengquan

Abstract excerpt

Lysobacter enzymogenes is a ubiquitous soil gammaproteobacterium that produces a broad-spectrum antifungal antibiotic, known as heat-stable antifungal factor (HSAF). To increase HSAF production for use against fungal crop diseases, it is important to understand how HSAF synthesis is regulated. To gain insights into transcriptional regulation of the HSAF synthesis gene cluster, we generated a library with deletion...

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Identifiers

PMID: 28087536
DOI: 10.1128/AEM.03397-16
PMCID: PMC5359478

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