Article

Identification of polyphosphate-binding proteins in <i>E. coli</i> uncovers targets involved in translation control and ribosome biogenesis

2025-02-14

Abstract excerpt

<h4>ABSTRACT</h4> In many bacteria, polyphosphate kinase (PPK) enzymes use ATP to synthesize polyphosphate (polyP) in response to cellular stress. These chains of inorganic phosphates are joined by high-energy bonds and can reach hundreds of residues in length. PolyP plays diverse functions in helping bacteria adjust to changing environmental conditions. However, the molecular mechanisms underlying these function...

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Literature Corpus work: 86fec27a-1a15-5ae3-96b1-bfe69042ded5
DOI: 10.1101/2025.02.12.637445

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