Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A proteomic and transcriptomic approach reveals new insight into beta-methylthiolation of Escherichia coli ribosomal protein S12.

Molecular & cellular proteomics : MCP - 1 Mar 2011

Strader Michael Brad, Costantino Nina, Elkins Christopher A, Chen Cai Yun, Patel Isha, Makusky Anthony J, Choy John S, Court Donald L, Markey Sanford P, Kowalak Jeffrey A

Abstract excerpt

β-methylthiolation is a novel post-translational modification mapping to a universally conserved Asp 88 of the bacterial ribosomal protein S12. This S12 specific modification has been identified on orthologs from multiple bacterial species. The origin and functional significance was investigated with both a proteomic strategy to identify candidate S12 interactors and expression microarrays to search for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspartic Acid
Share to Escherichia coli Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mass Spectrometry

Share to Peptides

Share to Proteomics

Share to Ribonucleoproteins

Share to Ribosomal Proteins

Share to Sulfhydryl Compounds

Source

Open in PubMed Open full text

Identifiers

PMID: 21169565
DOI: 10.1074/mcp.M110.005199
PMCID: PMC3047162

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A proteomic and transcriptomic approach reveals new insight into beta-methylthiolation of Escherichia coli ribosomal protein S12.PMID 21169565Read ↗

Functional characterization of the YmcB and YqeV tRNA methylthiotransferases of Bacillus subtilis.Semantic proximity Read ↗

Adaptive Remodeling of the Bacterial Proteome by Specific Ribosomal Modification Regulates Pseudomonas Infection and Niche Colonisation.Semantic proximity Read ↗

Suppression of a cold-sensitive mutation in ribosomal protein S5 reveals a role for RimJ in ribosome biogenesis.Semantic proximity Read ↗

Effects of streptomycin resistance mutations on posttranslational modification of ribosomal protein S12.Semantic proximity Read ↗

Functional importance of individual rRNA 2'-O-ribose methylations revealed by high-resolution phenotyping.Semantic proximity Read ↗

Thermus thermophilus L11 methyltransferase, PrmA, is dispensable for growth and preferentially modifies free ribosomal protein L11 prior to ribosome assembly.Semantic proximity Read ↗

Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA.Semantic proximity Read ↗

The functional proteome landscape of Escherichia coli.Semantic proximity Read ↗

Comparative anatomy of a regulatory ribosomal protein.Semantic proximity Read ↗

Error-prone and error-restrictive mutations affecting ribosomal protein S12.Semantic proximity Read ↗

The ribosomal l1 protuberance in yeast is methylated on a lysine residue catalyzed by a seven-beta-strand methyltransferase.Semantic proximity Read ↗

Escherichia coli rimM and yjeQ null strains accumulate immature 30S subunits of similar structure and protein complement.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.