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Article

PmrD is required for modifications to escherichia coli endotoxin that promote antimicrobial resistance.

Antimicrobial agents and chemotherapy - 1 Apr 2015

Rubin Erica J, Herrera Carmen M, Crofts Alexander A, Trent M Stephen

Abstract excerpt

In Salmonella enterica, PmrD is a connector protein that links the two-component systems PhoP-PhoQ and PmrA-PmrB. While Escherichia coli encodes a PmrD homolog, it is thought to be incapable of connecting PhoPQ and PmrAB in this organism due to functional divergence from the S. enterica protein. However, our laboratory previously observed that low concentrations of Mg(2+), a PhoPQ-activating signal, leads to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25605366
DOI: 10.1128/AAC.05052-14
PMCID: PMC4356761

Genes

CAMP

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