Article
Interleukin 1 beta (IL1ß) rs16944 genetic variant as a genetic marker of severe renal manifestations and renal sequelae in Henoch-Schönlein purpura.
Clinical and experimental rheumatology - 1 Jan 2000
López-Mejías Raquel, Genre Fernanda, Remuzgo-Martínez Sara, Sevilla Pérez Belen, Castañeda Santos, Llorca Javier, Ortego-Centeno Norberto, Ubilla Begoña, Mijares Verónica, Pina Trinitario, Calvo-Río Vanesa, Miranda-Filloy Jose A, Navas Parejo Antonio, Argila Diego, Sánchez-Pérez Javier, Rubio Esteban, Luque Manuel León, Blanco-Madrigal Juan María, Galíndez-Aguirregoikoa Eva, Martín Javier, Blanco Ricardo, González-Gay Miguel A
Abstract excerpt
OBJECTIVES: Data from a small series suggested that the Interleukin 1 beta (IL1ß) rs16944 polymorphism may be associated with severe renal involvement and persistent renal damage (renal sequelae) in Henoch-Schönlein purpura (HSP). To confirm this association, we assessed the largest cohort of Caucasian HSP patients ever considered for genetic studies. METHODS: 338 Spanish HSP patients and 635 sex and ethnically...
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