Article
Interleukin 1 receptor antagonist gene polymorphism is associated with severe renal involvement and renal sequelae in Henoch-Schönlein purpura.
The Journal of rheumatology - 1 Jul 2002
Amoli Mahsa M, Thomson Wendy, Hajeer Ali H, Calviño Maria C, Garcia-Porrua Carlos, Ollier William E R, Gonzalez-Gay Miguel A
Abstract excerpt
OBJECTIVE: To assess the influence of interleukin 1 receptor antagonist gene polymorphism (IL1RN) in the incidence of Henoch-Schönlein purpura (HSP) and cutaneous leukocytoclastic angiitis (CLA) and to determine if implications exist with severe systemic complications of HSP, in particular with severe renal involvement and permanent renal dysfunction (renal sequelae). METHODS: Patients from Northwest Spain with...
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