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Article

Interleukin Variants Are Associated with the Development and Progression of IgA Nephropathy: A Candidate-Gene Association Study and Meta-Analysis.

International journal of molecular sciences - 15 Nov 2023

Chronopoulou Ioanna, Tziastoudi Maria, Pissas Georgios, Dardiotis Efthimios, Dardioti Maria, Golfinopoulos Spyridon, Filippidis Georgios, Mertens Peter R, Tsironi Evangelia E, Liakopoulos Vassilios, Eleftheriadis Theodoros, Stefanidis Ioannis

Abstract excerpt

The interleukin-1 gene cluster encodes cytokines, which modulate mesangial cell proliferation and matrix expansion, both constituting central factors in the development and progression of immunoglobulin A nephropathy (IgAN). A candidate-gene study was performed to examine the association of polymorphisms of the interleukin-1 gene cluster with the risk of progressive IgAN. To gain deeper insights into the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38003536
DOI: 10.3390/ijms242216347
PMCID: PMC10671103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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