Article
Polymorphism at codon 469 of the intercellular adhesion molecule-1 locus is associated with protection against severe gastrointestinal complications in Henoch-Schönlein purpura.
The Journal of rheumatology - 1 May 2001
Amoli M M, Mattey D L, Calviño M C, Garcia-Porrua C, Thomson W, Hajeer A H, Ollier W E, Gonzalez-Gay M A
Abstract excerpt
OBJECTIVE: Henoch-Schonlein purpura (HSP) is a small sized vasculitis affecting mainly children. Intercellular adhesion molecule-1 (ICAM-1) gene polymorphisms have recently been implicated in the susceptibility to some vasculitides. To further investigate the clinical implication of ICAM-1 polymorphisms in HSP, we examined their potential association and influence in the development of severe complications in an...
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