CT Imaging Phenotypes of Pulmonary Fibrosis in the MUC5B Promoter Site Polymorphism.

doi:10.1016/j.chest.2015.11.009

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Article

CT Imaging Phenotypes of Pulmonary Fibrosis in the MUC5B Promoter Site Polymorphism.

Chest - 1 May 2016

Chung Jonathan H, Peljto Anna L, Chawla Ashish, Talbert Janet L, McKean David F, Rho Byung-Hak, Fingerlin Tasha E, Schwarz Marvin I, Schwartz David A, Lynch David A

Abstract excerpt

BACKGROUND: To determine the effect of the MUC5B promoter polymorphism (rs35705950) on the CT imaging appearance of pulmonary fibrosis. METHODS: High-resolution CT scans of 1,764 subjects were scored as part of a, genomewide association study with institutional review board approval; 1,491 of these had pulmonary fibrosis on CT scans and were included in the study. Two thoracic radiologists independently scored CT...

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Identifiers

PMID: 26836909
DOI: 10.1016/j.chest.2015.11.009
PMCID: PMC4944767

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