Article
Proportion of idiopathic pulmonary fibrosis risk explained by known genetic loci
2020-08-15
Abstract excerpt
Genome-wide association studies have identified 14 genetic loci associated with susceptibility to idiopathic pulmonary fibrosis (IPF), a devastating lung disease with poor prognosis. Of these, the variant with the strongest association, rs35705950, is located in the promoter region of the MUC5B gene and has a risk allele (T) frequency of 30-35% in IPF cases. Here we present estimates of the proportion of disease l...
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Identifiers and source
- Literature Corpus work
- 8a14f114-0813-5e3c-a4be-025135347776
- DOI
- 10.1101/2020.08.14.20172528