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Article

Radiological Assessment in Idiopathic Pulmonary Fibrosis (IPF) Patients According to MUC5B Polymorphism.

International journal of molecular sciences - 14 Dec 2022

Cocconcelli Elisabetta, Bernardinello Nicol, Giraudo Chiara, Castelli Gioele, Greco Clorinda, Polverosi Roberta, Saetta Marina, Spagnolo Paolo, Balestro Elisabetta

Abstract excerpt

The MUC5B rs35705950 mutant T allele is the strongest genetic risk factor for familial and sporadic IPF. We sought to determine whether MUC5B genotype influences radiological patterns of IPF at diagnosis, as well as their change over time, in patients on antifibrotic therapy. Among eighty-eight IPF patients, previously genotyped for MUC5B rs35705950, we considered seventy-eight patients who were evaluated for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease
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Identifiers

PMID: 36555528
DOI: 10.3390/ijms232415890
PMCID: PMC9784960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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