Article
Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex.
Journal of psychiatric research - 1 Sept 2013
Guella Ilaria, Sequeira Adolfo, Rollins Brandi, Morgan Linda, Torri Federica, van Erp Theo G M, Myers Richard M, Barchas Jack David, Schatzberg Alan F, Watson Stanley J, Akil Huda, Bunney William E, Potkin Steven G, Macciardi Fabio, Vawter Marquis P
Abstract excerpt
MicroRNAs (miRNAs) are small non-coding RNAs that act as potent regulators of gene expression. A recent GWAS reported the rs1625579 SNP, located downstream of miR-137, as the strongest new association with schizophrenia [Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, et al. Genome-wide association study identifies five new schizophrenia loci. Nat Genet 2011;43:969-76.]. Prior to this GWAS...
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