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Article

Alcohol Drinking Mediates the Association between Polymorphisms of ADH1B and ALDH2 and Hepatitis B-Related Hepatocellular Carcinoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2016

Liu Jessica, Yang Hwai-I, Lee Mei-Hsuan, Jen Chin-Lan, Hu Hui-Han, Lu Sheng-Nan, Wang Li-Yu, You San-Lin, Huang Yen-Tsung, Chen Chien-Jen

Abstract excerpt

BACKGROUND: The role of polymorphisms on ADH1B and ALDH2 in patients with chronic hepatitis B is unclear. This study aims to examine whether alcohol drinking mediates the association between two ADH1B and ALDH2 polymorphisms and the risk of hepatocellular carcinoma among chronic hepatitis B patients. METHODS: A total of 3,824 individuals were enrolled in this study. Two SNPs, rs1229984 (ADH1B) and rs671 (ALDH2),...

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Topics

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Share to Alcohol Dehydrogenase
Share to Alcohol Drinking
Share to Aldehyde Dehydrogenase, Mitochondrial
Share to Carcinoma, Hepatocellular
Share to Cohort Studies
Share to Hepatitis B
Share to Liver Neoplasms
Share to Polymorphism, Genetic

Source

Identifiers

PMID: 26827895
DOI: 10.1158/1055-9965.EPI-15-0961

Genes

ALDH2
IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Alcohol Drinking Mediates the Association between Polymorphisms of ADH1B and ALDH2 and Hepatitis B-Related Hepatocellular Carcinoma.PMID 26827895Read ↗

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