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[Mechanism of salidroside in inhibiting proliferation, migration and promoting phenotypic switching of arterial smooth muscle cells].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica - 1 Jun 2024

Zhang Yong-Jie, Yan Zhi-Gang, Lin Fei, Liu Hui-Bing, Zhao Guo-An

Abstract excerpt

This study aims to examine the effect of salidroside(SAL) on the phenotypic switching of human aortic smooth muscle cells(HASMC) induced by the platelet-derived growth factor-BB(PDGF-BB) and investigate the pharmacological mechanism. Firstly, the safe concentration of SAL was screened by the lactate dehydrogenase release assay. HASMC were divided into control, model, and SAL groups, and the cells in other groups...

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PMID: 39041099
DOI: 10.19540/j.cnki.cjcmm.20240325.201

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