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Article

Rad61/Wpl1 (Wapl), a cohesin regulator, controls chromosome compaction during meiosis.

Nucleic acids research - 20 Apr 2016

Challa Kiran, Lee Min-Su, Shinohara Miki, Kim Keun P, Shinohara Akira

Abstract excerpt

Meiosis-specific cohesin, required for the linking of the sister chromatids, plays a critical role in various chromosomal events during meiotic prophase I, such as chromosome morphogenesis and dynamics, as well as recombination. Rad61/Wpl1 (Wapl in other organisms) negatively regulates cohesin functions. In this study, we show that meiotic chromosome axes are shortened in the budding yeast rad61/wpl1 mutant,...

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Share to Chromosomal Proteins, Non-Histone
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Recombination, Genetic

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Source

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Identifiers

PMID: 26825462
DOI: 10.1093/nar/gkw034
PMCID: PMC4838362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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