Article
RANK/RANKL/OPG pathway: genetic associations with stress fracture period prevalence in elite athletes.
Bone - 1 Feb 2015
Varley Ian, Hughes David C, Greeves Julie P, Stellingwerff Trent, Ranson Craig, Fraser William D, Sale Craig
Abstract excerpt
CONTEXT: The RANK/RANKL/OPG signalling pathway is important in the regulation of bone turnover, with single nucleotide polymorphisms (SNPs) in genes within this pathway associated with bone phenotypic adaptations. OBJECTIVE: To determine whether four SNPs associated with genes in the RANK/RANKL/OPG signalling pathway were associated with stress fracture injury in elite athletes. DESIGN, PARTICIPANTS, AND METHODS:...
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