Article
CD40 -1C>T polymorphism and the risk of lung cancer in a Chinese population.
International journal of clinical and experimental pathology - 1 Jan 2015
Zhou Gang, Wang Ying, Fang Ziyao, Liu Rongrong, Wang Anhui, Zhao Feng, Chen Lihua
Abstract excerpt
BACKGROUND: The co-stimulatory molecule CD40 plays an important role in anti-tumor responses by promoting cytotoxic T lymphocyte (CTL) activity and differentiation of helper T cells. Growing evidence suggests that single nucleotide polymorphisms (SNPs) in CD40 are associated with the susceptibility to cancer. This study investigated the association between the CD40 -1C/T SNP (rs1883832) and lung cancer in a...
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