Transforming growth factor-β1 rs1800470 polymorphism is associated with lung cancer risk: a meta-analysis.

doi:10.12659/MSM.891122

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Article

Transforming growth factor-β1 rs1800470 polymorphism is associated with lung cancer risk: a meta-analysis.

Medical science monitor : international medical journal of experimental and clinical research - 20 Nov 2014

Fan Huizhen, Yu Huapeng, Deng Huojin, Chen Xin

Abstract excerpt

BACKGROUND: Transforming growth factor-β1 is a member of a large class of polypeptides that regulate the proliferation, differentiation, and carcinogenesis of epithelial cells. The rs1800470 polymorphism influences transforming growth factor-β1 expression and has been associated with lung cancer susceptibility. However, the association between the rs1800470 polymorphism and lung cancer risk remains controversial....

Topics

Aged
Case-Control Studies
Female
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Lung Neoplasms
Male
Middle Aged
Polymorphism, Single Nucleotide
Risk Factors
Transforming Growth Factor beta1

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Identifiers

PMID: 25409890
DOI: 10.12659/MSM.891122
PMCID: PMC4247234

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