Article
Group A Streptococcus exploits human plasminogen for bacterial translocation across epithelial barrier via tricellular tight junctions
29 Jan 2016
Abstract excerpt
Group A Streptococcus (GAS) is a human-specific pathogen responsible for local suppurative and life-threatening invasive systemic diseases. Interaction of GAS with human plasminogen (PLG) is a salient characteristic for promoting their systemic dissemination. In the present study, a serotype M28 strain was found predominantly localized in tricellular tight junctions of epithelial cells cultured in the presence of...
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