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Group A <i>Streptococcus</i> remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and dissemination

2023-10-04

Abstract excerpt

Group A Streptococcus (GAS) is a Gram-positive bacterial pathogen that causes a wide spectrum of illnesses ranging from pharyngitis and rheumatic fever to more invasive and severe diseases such as necrotizing fasciitis and toxic shock syndrome. Invasive outcomes of GAS infections often result from entry of the bacteria via an open wound into tissue and blood systems. The coagulation cascade serves as an innate de...

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Identifiers and source

Literature Corpus work
7cc09bf5-dc97-5beb-982f-afc94eaeb879
DOI
10.1101/2023.10.04.560727
Open publication

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Group A <i>Streptococcus</i> remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and disseminationDOI 10.1101/2023.10.04.560727
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