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Article

Multiple microRNA regulation of lipoprotein lipase gene abolished by 3'UTR polymorphisms in a triglyceride-lowering haplotype harboring p.Ser474Ter.

Atherosclerosis - 1 Mar 2016

Caussy Cyrielle, Charrière Sybil, Meirhaeghe Aline, Dallongeville Jean, Lefai Etienne, Rome Sophie, Cuerq Charlotte, Euthine Vanessa, Delay Mireille, Marmontel Oriane, Di Filippo Mathilde, Lagarde Michel, Moulin Philippe, Marçais Christophe

Abstract excerpt

BACKGROUND: Lipoprotein lipase (LPL) is a key enzyme in triglyceride (TG) metabolism. LPL gene single nucleotide polymorphisms (SNPs) are associated with TG concentrations however the functionality of many of these SNPs remains poorly understood. MicroRNAs (miR) exert post-transcriptional down-regulation and their target sequence on the 3'UTR may be altered by SNPs. We therefore investigated whether LPL 3'UTR...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26820803
DOI: 10.1016/j.atherosclerosis.2016.01.010

Genes

LPL

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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