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Article

The -514 C->T hepatic lipase promoter region polymorphism and plasma lipids: a meta-analysis.

The Journal of clinical endocrinology and metabolism - 1 Aug 2004

Isaacs Aaron, Sayed-Tabatabaei Fakhredin A, Njajou Omer T, Witteman Jacqueline C M, van Duijn Cornelia M

Abstract excerpt

Investigations of the -514 C-->T single nucleotide polymorphism (SNP) in the hepatic lipase (HL) gene promoter region (LIPC) have yielded contradictory results regarding its association with changes in plasma lipids. The current study is a meta-analysis of 25 publications on this SNP, comprising over 24,000 individuals, and its relationship with total cholesterol, low-density lipoprotein cholesterol, high-density...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15292318
DOI: 10.1210/jc.2004-0188

Genes

LIPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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