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Article

MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Jan 2016

Haque Khujista, Pandey Atul K, Zheng Hong-Wei, Riazuddin Saima, Sha Su-Hua, Puligilla Chandrakala

Abstract excerpt

Mechanosensory hair cells (HCs) residing in the inner ear are critical for hearing and balance. Precise coordination of proliferation, sensory specification, and differentiation during development is essential to ensure the correct patterning of HCs in the cochlear and vestibular epithelium. Recent studies have revealed that FGF20 signaling is vital for proper HC differentiation. However, the mechanisms by which...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Evoked Potentials, Auditory, Brain Stem

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Source

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Identifiers

PMID: 26818521
DOI: 10.1523/JNEUROSCI.1853-15.2016
PMCID: PMC4728730

Genes

FGF20
FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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