Article
A network based covariance test for detecting multivariate eQTL in saccharomyces cerevisiae.
BMC systems biology - 11 Jan 2016
Yuan Huili, Li Zhenye, Tang Nelson L S, Deng Minghua
Abstract excerpt
BACKGROUND: Expression quantitative trait locus (eQTL) analysis has been widely used to understand how genetic variations affect gene expressions in the biological systems. Traditional eQTL is investigated in a pair-wise manner in which one SNP affects the expression of one gene. In this way, some associated markers found in GWAS have been related to disease mechanism by eQTL study. However, in real life,...
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