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Article

Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis.

BMC bioinformatics - 20 May 2008

Biswas Shameek, Storey John D, Akey Joshua M

Abstract excerpt

BACKGROUND: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, most studies have searched for eQTL by analyzing gene expression traits one at a time. As thousands of expression traits are typically analyzed, this can reduce power because of the need to correct for the number of hypothesis tests...

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Identifiers

PMID: 18492285
DOI: 10.1186/1471-2105-9-244
PMCID: PMC2424053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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