Article
Statistical analysis reveals co-expression patterns of many pairs of genes in yeast are jointly regulated by interacting loci.
PLoS genetics - 1 Mar 2013
Wang Lin, Zheng Wei, Zhao Hongyu, Deng Minghua
Abstract excerpt
Expression quantitative trait loci (eQTL) studies have generated large amounts of data in different organisms. The analyses of these data have led to many novel findings and biological insights on expression regulations. However, the role of epistasis in the joint regulation of multiple genes has not been explored. This is largely due to the computational complexity involved when multiple traits are...
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