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Article

Inferring Gene Regulatory Networks from a Population of Yeast Segregants.

Scientific reports - 4 Feb 2019

Chen Chen, Zhang Dabao, Hazbun Tony R, Zhang Min

Abstract excerpt

Constructing gene regulatory networks is crucial to unraveling the genetic architecture of complex traits and to understanding the mechanisms of diseases. On the basis of gene expression and single nucleotide polymorphism data in the yeast, Saccharomyces cerevisiae, we constructed gene regulatory networks using a two-stage penalized least squares method. A large system of structural equations via optimal...

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Identifiers

PMID: 30718595
DOI: 10.1038/s41598-018-37667-4
PMCID: PMC6361976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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