Article
Inferring Gene Regulatory Networks from a Population of Yeast Segregants.
Scientific reports - 4 Feb 2019
Chen Chen, Zhang Dabao, Hazbun Tony R, Zhang Min
Abstract excerpt
Constructing gene regulatory networks is crucial to unraveling the genetic architecture of complex traits and to understanding the mechanisms of diseases. On the basis of gene expression and single nucleotide polymorphism data in the yeast, Saccharomyces cerevisiae, we constructed gene regulatory networks using a two-stage penalized least squares method. A large system of structural equations via optimal...
Topics
- Chromosome Mapping
- Gene Expression
- Gene Expression Regulation
- Gene Ontology
- Gene Regulatory Networks
- Least-Squares Analysis
- Models, Genetic
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci
- Saccharomyces cerevisiae
- Sequence Analysis, DNA