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Article

Trait-trait dynamic interaction: 2D-trait eQTL mapping for genetic variation study.

BMC genomics - 23 May 2008

Sun Wei, Yuan Shinsheng, Li Ker-Chau

Abstract excerpt

BACKGROUND: Many studies have shown that the abundance level of gene expression is heritable. Analogous to the traditional genetic study, most researchers treat the expression of one gene as a quantitative trait and map it to expression quantitative trait loci (eQTL). This is 1D-trait mapping. 1D-trait mapping ignores the trait-trait interaction completely, which is a major shortcoming. RESULTS: To overcome this...

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Identifiers

PMID: 18498664
DOI: 10.1186/1471-2164-9-242
PMCID: PMC2432080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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