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Article

Mitofusin-2 gene polymorphisms and metabolic dysfunction associated fatty liver disease: a case-control study in a Chinese population.

The Journal of international medical research - 1 Jul 2023

Yuan Xiwei, Hou Mengmeng, Wang Yiqi, Zhang Siyu, Li Lu, Mi Yingjun, Du Huijuan, Yu Songhao, Nan Yuemin

Abstract excerpt

OBJECTIVES: Mitofusion-2 (Mfn2) may have a role in mitochondrial oxidative stress and insulin resistance that can promote the development of metabolic dysfunction associated fatty liver disease (MAFLD). This retrospective and case control study aimed to explore the relationships between common Mfn2 single nucleotide polymorphisms (SNPs) and MAFLD in a northern Han Chinese population. METHODS: Six Mfn2 SNPs...

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Identifiers

PMID: 37522325
DOI: 10.1177/03000605231187953
PMCID: PMC10392247

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