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Article

Haplotype of smoothelin gene associated with essential hypertension.

Hereditas - 1 Oct 2012

Jiang Jie, Nakayama Tomohiro, Shimodaira Masanori, Sato Naoyuki, Aoi Noriko, Sato Mikano, Izumi Yoichi, Kasamaki Yuji, Ohta Masakatsu, Soma Masayoshi, Matsumoto Koichi, Kawamura Hiroshi, Ozawa Yukio, Ma Yitong

Abstract excerpt

Smoothelin is a specific cytoskeletal protein that is associated with smooth muscle cells. The human SMTN gene encodes smoothelin-A and smoothelin-B, and studies using SMTN gene knockout mice have demonstrated that these animals develop hypertension. The aim of the present study was to investigate the association between the human SMTN gene and essential hypertension (EH) using a haplotype-based case-control...

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Source

Identifiers

PMID: 23121329
DOI: 10.1111/j.1601-5223.2012.02242.x

Genes

SMTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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