Article
Inactivation of Francisella tularensis Gene Encoding Putative ABC Transporter Has a Pleiotropic Effect upon Production of Various Glycoconjugates.
Journal of proteome research - 5 Feb 2016
Dankova Vera, Balonova Lucie, Link Marek, Straskova Adela, Sheshko Valeria, Stulik Jiri
Abstract excerpt
Francisella tularensis, an intracellular pathogen causing the disease tularemia, utilizes surface glycoconjugates such as lipopolysaccharide, capsule, and capsule-like complex for its protection against inhospitable conditions of the environment. Francisella species also possess a functional glycosylation apparatus by which specific proteins are O-glycosidically modified. We here created a mutant with a...
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