Article
Host-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity.
PloS one - 1 Jan 2011
Zarrella Tiffany M, Singh Anju, Bitsaktsis Constantine, Rahman Tabassum, Sahay Bikash, Feustel Paul J, Gosselin Edmund J, Sellati Timothy J, Hazlett Karsten R O
Abstract excerpt
BACKGROUND: The gram-negative bacterium Francisella tularensis survives in arthropods, fresh water amoeba, and mammals with both intracellular and extracellular phases and could reasonably be expected to express distinct phenotypes in these environments. The presence of a capsule on this bacterium has been controversial with some groups finding such a structure while other groups report that no capsule could be...
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