Article
Hemoglobin E Prevalence among Ethnic Groups Residing in Malaria-Endemic Areas of Northern Thailand and Its Lack of Association with Plasmodium falciparum Invasion In Vitro.
PloS one - 1 Jan 2016
Lithanatudom Pathrapol, Wipasa Jiraprapa, Inti Pitsinee, Chawansuntati Kriangkrai, Svasti Saovaros, Fucharoen Suthat, Kangwanpong Daoroong, Kampuansai Jatupol
Abstract excerpt
Hemoglobin E (HbE) is one of the most common hemoglobin variants caused by a mutation in the β-globin gene, and found at high frequencies in various Southeast Asian groups. We surveyed HbE prevalence among 8 ethnic groups residing in 5 villages selected for their high period malaria endemicity, and 5 for low endemicity in northern Thailand, in order to uncover factors which may affect genetic persistence of HbE...
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